Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | RRM1 | P23921 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10777307 | 0.89 | SPHK1 (0.48) | LMNACYP2D6SPHK1TP53GMNN | |
| SCHEMBL7156689 | 0.87 | LMNA (0.53) | LMNACYP2D6SPHK1TP53GMNN | |
| SCHEMBL27421723 | 0.87 | LMNA (0.53) | LMNACYP2D6SPHK1TP53GMNN | |
| Bromide SCHEMBL28057170 | 0.85 | LMNA (0.52) | LMNACYP2D6SPHK1TP53GMNN | |
| SCHEMBL20142346 | 0.85 | DNM1 (0.48) | LMNACYP2D6SPHK1TP53GMNN | |
| Hydrochloric Acid SCHEMBL5350915 | 0.85 | LMNA (0.52) | LMNACYP2D6SPHK1TP53GMNN | |
| Hydrochloric Acid SCHEMBL5353819 | 0.85 | LMNA (0.52) | LMNACYP2D6SPHK1TP53GMNN | |
| SCHEMBL9817588 | 0.81 | SPHK1 (0.45) | LMNACYP2D6SPHK1TP53GMNN | |
| Fluoride SCHEMBL28034068 | 0.81 | DNM1 (0.54) | LMNACYP2D6SPHK1TP53GMNN | |
| SCHEMBL14900909 | 0.78 | OPRM1 (0.52) | LMNACYP2D6SPHK1TP53GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023074-A | Containing polyoxyethylene glycol to prevent phase separation | COLGATE-PALMOLIVE COMPANY (US) | 1991-06-11 | — | — | US | disclosed |