Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 3/20 | 0.60 |
| ▸ | WNT3A | P56704 | 3/20 | 0.60 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.58 |
| ▸ | CDK2 | P24941 | 1/20 | 0.58 |
| ▸ | FLT3 | P36888 | 1/20 | 0.58 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.54 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.52 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29444537 | 0.93 | FLT3 (0.65) | CTNNB1WNT3ACCNA2CDK2FLT3 | |
| SCHEMBL42245 | 0.93 | FLT3 (0.65) | CTNNB1WNT3ACCNA2CDK2FLT3 | |
| SCHEMBL27541852 | 0.91 | FLT3 (0.63) | CTNNB1WNT3ACCNA2CDK2FLT3 | |
| Hydrochloric Acid SCHEMBL4258298 | 0.91 | FLT3 (0.63) | CTNNB1WNT3ACCNA2CDK2FLT3 | |
| Hydrazine SCHEMBL27690059 | 0.89 | FLT3 (0.61) | CTNNB1WNT3ACCNA2CDK2FLT3 | |
| Hydrazine SCHEMBL27956766 | 0.88 | FLT3 (0.59) | CTNNB1WNT3ACCNA2CDK2FLT3 | |
| Benzamide SCHEMBL27732371 | 0.82 | CTNNB1 (0.60) | CTNNB1WNT3ACCNA2CDK2FLT3 | |
| SCHEMBL4464792 | 0.81 | KDM4E (0.68) | CTNNB1WNT3ACCNA2CDK2FLT3 | |
| SCHEMBL5908296 | 0.81 | KDM4E (0.57) | CTNNB1WNT3ACCNA2CDK2FLT3 | |
| SCHEMBL591861 | 0.80 | KDM4E (0.62) | CTNNB1WNT3ACCNA2CDK2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103154018-B | For passing through the antibody of affinity chromatography and the part of Fc-fusion protein purification | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2016-04-27 | — | — | CN | disclosed |