Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.65 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.65 |
| ▸ | CDK2 | P24941 | 1/20 | 0.65 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.64 |
| ▸ | STAT3 | P40763 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.63 |
| ▸ | WNT3A | P56704 | 3/20 | 0.63 |
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.55 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42245 | 1.00 | FLT3 (0.65) | FLT3CCNA2CDK2CCNA1KDM4E | |
| Hydrochloric Acid SCHEMBL4258298 | 0.98 | FLT3 (0.63) | FLT3CCNA2CDK2CCNA1KDM4E | |
| SCHEMBL27541852 | 0.98 | FLT3 (0.63) | FLT3CCNA2CDK2CCNA1KDM4E | |
| Hydrazine SCHEMBL27690059 | 0.96 | FLT3 (0.61) | FLT3CCNA2CDK2CCNA1KDM4E | |
| Hydrazine SCHEMBL27956766 | 0.94 | FLT3 (0.59) | FLT3CCNA2CDK2CCNA1KDM4E | |
| Methylene Chloride SCHEMBL28057236 | 0.93 | CTNNB1 (0.60) | FLT3CCNA2CDK2CCNA1KDM4E | |
| Benzamide SCHEMBL27732371 | 0.88 | CTNNB1 (0.60) | FLT3CCNA2CDK2CCNA1KDM4E | |
| SCHEMBL4464792 | 0.87 | KDM4E (0.68) | FLT3CCNA2CDK2CCNA1KDM4E | |
| SCHEMBL5908296 | 0.87 | KDM4E (0.57) | FLT3CCNA2CDK2CCNA1KDM4E | |
| Indole SCHEMBL9100070 | 0.86 | FLT3 (0.51) | FLT3CCNA2CDK2CCNA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403577-B | Synthesis method of carboxyl azaindole | 西安宇特邦医药科技有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-115403577-A | Synthesis method of carboxyl azaindole | 凤翔万生源医药科技有限公司 | 2022-11-29 | — | — | CN | claimed |
| WO-2022120372-A1 | SALTS OF A HETEROCYCLIC COMPOUND AND CRYSTALLINE FORMS, PROCESSES FOR PREPARING, THERAPEUTIC USES, AND PHARMACEUTICAL COMPOSITIONS THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-06-09 | — | — | WO | claimed |
| EP-4692215-A1 | MODIFIED POLYOLEFIN RESIN COMPOSITION AND USE FOR SAID RESIN COMPOSITION | TOYOBO MC Corporation (JP) | 2026-02-11 | — | — | EP | disclosed |
| EP-4612146-A1 | AHR AGONISTS | Eli Lilly and Company (US) | 2025-09-10 | — | — | EP | disclosed |
| CN-114846014-B | Insect repellent compounds comprising azaindole structures | 英特维特国际股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| WO-2024203664-A1 | MODIFIED POLYOLEFIN RESIN COMPOSITION AND USE FOR SAID RESIN COMPOSITION | 東洋紡エムシー株式会社 | 2024-10-03 | — | — | WO | disclosed |
| CN-114867718-B | Indazole derivatives and use thereof | 韩国化学研究院 | 2024-10-01 | — | — | CN | disclosed |
| CN-115403577-B | Synthesis method of carboxyl azaindole | 西安宇特邦医药科技有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-115403577-B | Synthesis method of carboxyl azaindole | 西安宇特邦医药科技有限公司 | 2024-04-26 | — | — | CN | disclosed |
| WO-2022235715-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING ITK, COMPOSITIONS, COMPRISING THE SAME METHODS OF THEIR MAKING AND METHODS OF THEIR USE | NURIX THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| WO-2022235698-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING TARGET PROTEINS, COMPOSITIONS, COMPRISING THE SAME, METHODS OF THEIR MAKING, AND METHODS OF THEIR USE | NURIX THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| EP-4077322-A1 | ANTHELMINTIC COMPOUNDS COMPRISING AZAINDOLES STRUCTURE | Intervet International B.V. (NL) | 2022-10-26 | — | — | EP | disclosed |
| WO-2022212568-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING LIPID METABOLISM | 1BASE PHARMACEUTICALS, LLC (US) | 2022-10-06 | — | — | WO | disclosed |
| CN-114846014-A | Insect repellent compounds comprising azaindole structures | 英特维特国际股份有限公司 | 2022-08-02 | — | — | CN | disclosed |
| WO-2022130171-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS INHIBITORS OF ITK FOR THE TREATMENT OF SKIN DISEASE | PFIZER INC. (US) | 2022-06-23 | — | — | WO | disclosed |
| EP-3990433-A1 | PROCESSES OF MAKING 2-((1-BENZYL-1H-INDAZOL-3-YL)METHOXY)-2-METHYLPROPANOIC ACID AND ITS DERIVATIVES | Translatum Medicus Inc. (CA) | 2022-05-04 | — | — | EP | disclosed |
| EP-3986477-A1 | CONJUGATES OF pi-ELECTRON-PAIR-DONATING HETEROAROMATIC NITROGEN-COMPRISING COMPOUNDS | Ascendis Pharma A/S (DK) | 2022-04-27 | — | — | EP | disclosed |
| CN-108884096-B | Spiroindolinones as DDR1 inhibitors | 豪夫迈·罗氏有限公司 | 2022-03-22 | — | — | CN | disclosed |