SCHEMBL42245

SCHEMBL42245

O=C(O)c1n[nH]c2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 2/20 0.65
CCNA2 P20248 1/20 0.65
CDK2 P24941 1/20 0.65
CCNA1 P78396 1/20 0.65
KDM4E B2RXH2 5/20 0.64
YTHDC1 Q96MU7 1/20 0.64
STAT3 P40763 1/20 0.64
HIF1A Q16665 1/20 0.64
CTNNB1 P35222 3/20 0.63
WNT3A P56704 3/20 0.63
IDO1 P14902 1/20 0.61
MAP2K4 P45985 2/20 0.57
NPC1 O15118 4/20 0.56
RAB9A P51151 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
ALDH1A1 P00352 1/20 0.56
HAO1 Q9UJM8 1/20 0.55
EPHB3 P54753 1/20 0.54
MAPK1 P28482 1/20 0.53
MAPKAPK3 Q16644 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29444537 1.00 FLT3 (0.65) FLT3CCNA2CDK2CCNA1KDM4E
Hydrochloric Acid SCHEMBL4258298 0.98 FLT3 (0.63) FLT3CCNA2CDK2CCNA1KDM4E
SCHEMBL27541852 0.98 FLT3 (0.63) FLT3CCNA2CDK2CCNA1KDM4E
Hydrazine SCHEMBL27690059 0.96 FLT3 (0.61) FLT3CCNA2CDK2CCNA1KDM4E
Hydrazine SCHEMBL27956766 0.94 FLT3 (0.59) FLT3CCNA2CDK2CCNA1KDM4E
Methylene Chloride SCHEMBL28057236 0.93 CTNNB1 (0.60) FLT3CCNA2CDK2CCNA1KDM4E
Benzamide SCHEMBL27732371 0.88 CTNNB1 (0.60) FLT3CCNA2CDK2CCNA1KDM4E
SCHEMBL4464792 0.87 KDM4E (0.68) FLT3CCNA2CDK2CCNA1KDM4E
SCHEMBL5908296 0.87 KDM4E (0.57) FLT3CCNA2CDK2CCNA1KDM4E
Indole SCHEMBL9100070 0.86 FLT3 (0.51) FLT3CCNA2CDK2CCNA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2493 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036679-A Preparation method and application of indazole carboxylic acid 广东大丰植保科技有限公司 2026-05-15 CN claimed
CN-122036615-A Indazole hydrazide compound and preparation method and application thereof 南京农业大学 2026-05-15 CN claimed
US-20250269031-A1 MITOCHONDRIA TARGETING QUINOLINIUM-DRUG CONJUGATES AND THEIR SELF-ASSEMBLING NANOFORMULATIONS FOR CANCER THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-08-28 US claimed
CN-119433638-A Promoter for alkaline platinization 重庆立道新材料科技有限公司 2025-02-14 CN claimed
CN-119192873-A Sound insulation fireproof plate 杭州鋆成建筑装饰工程有限公司 2024-12-27 CN claimed
CN-118206490-B Indazole-3-carboxylic acid derivative with antitumor activity, preparation method and application 国王医学科技(山东)有限公司 2024-11-15 CN claimed
CN-118814174-A Post-pickling lotion applied to fine circuit and application method 南雄市溢诚化工有限公司 2024-10-22 CN claimed
CN-118598903-A Indazole-3-carboxylic acid organotin carboxylate complex, and preparation method and application thereof 衡阳师范学院 2024-09-06 CN claimed
CN-118203009-A Application of indazole-3-carboxylic acid in preventing and treating plant bacterial diseases 中国热带农业科学院环境与植物保护研究所 2024-06-18 CN claimed
CN-118206490-A Indazole-3-carboxylic acid derivative with antitumor activity, preparation method and application 国王医学科技(山东)有限公司 2024-06-18 CN claimed
WO-1994027627-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1994-12-08 WO claimed
EP-0621788-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1994-11-02 EP claimed
WO-1993013789-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1993-07-22 WO claimed
EP-0498466-A1 Indazole-3-carboxamide and -3-carboxylic acid derivatives BEECHAM GROUP PLC (GB) 1992-08-12 EP claimed
US-5017573-A Serotonin receptor antagonist DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1991-05-21 US claimed
EP-0358903-A2 Indazole-3-carboxylic acid derivatives DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1990-03-21 EP claimed
EP-0350130-A2 New substituted 1,7-annelated 1H-indazoles DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1990-01-10 EP claimed
EP-0214158-A1 ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS THE UPJOHN COMPANY (US) 1987-03-18 EP claimed
EP-0200444-A2 Azabicyclononyl-indazole-carboxamide having 5-HT antagonist activity BEECHAM GROUP PLC (GB) 1986-11-05 EP claimed
WO-1986004582-A1 ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS THE UPJOHN COMPANY (US) 1986-08-14 WO claimed