Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.45 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CBS | P35520 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30330184 | 1.00 | CYP19A1 (0.50) | CYP19A1CYP1A1CYP1A2CYP1B1SLC5A1 | |
| SCHEMBL28286221 | 0.81 | NPC1 (0.54) | SLC5A1SLC5A2 | |
| SCHEMBL2188208 | 0.79 | KDM4E (0.53) | CYP19A1MAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL28721233 | 0.75 | CYP19A1 (0.56) | CYP19A1CYP1A1CYP1A2CYP1B1POLB | |
| SCHEMBL6790873 | 0.74 | CYP3A4 (0.51) | POLBCYP3A4 | |
| SCHEMBL16430754 | 0.74 | CYP19A1 (0.64) | CYP19A1CYP1A2SMN1; SMN2 | |
| SCHEMBL177102 | 0.73 | CYP26A1 (0.47) | CYP19A1MAPTSMN1; SMN2CALM1 | |
| SCHEMBL18214339 | 0.70 | CYP3A4 (0.78) | CYP1A2POLBMAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL3366271 | 0.69 | OPRD1 (0.62) | POLBMAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL2314134 | 0.69 | OPRD1 (0.62) | POLBMAPTKDM4EGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106038799-A | Pharmaceutical composition capable of treating cervical cancer and preparation method of pharmaceutical composition | 济南星懿医药技术有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-106038823-A | Pharmaceutical composition capable of treating breast cancer at advanced stage | 济南星懿医药技术有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-106038797-A | Pharmaceutical composition for preventing and treating bladder cancer | 济南星懿医药技术有限公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-105663248-A | Depression treating pharmaceutical composition | 济南星懿医药技术有限公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-105641219-A | Pharmaceutical composition for treating depression | 济南星懿医药技术有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-105596426-A | Pharmaceutical composition for treating schizophrenia | JINAN XINGYI MED TECH CO LTD | 2016-05-25 | — | — | CN | disclosed |
| CN-105560866-A | Medicine composition for preventing and treating benign prostatic hyperplasia and preparation method thereof | JINAN XINGYI MED TECH CO LTD | 2016-05-11 | — | — | CN | disclosed |
| CN-105560486-A | Pharmaceutical composition for treating schizophrenia | JINAN XINGYI MED TECH CO LTD | 2016-05-11 | — | — | CN | disclosed |
| CN-105535092-A | Medicine composition for treating prostatic hyperplasia | JINAN XINGYI MED TECH CO LTD | 2016-05-04 | — | — | CN | disclosed |
| CN-105535042-A | Medicine composition for treating benign prostatic hyperplasia | JINAN XINGYI MED TECH CO LTD | 2016-05-04 | — | — | CN | disclosed |
| CN-105535226-A | Medicine composition for treating esophagus cancer and preparation method thereof | JINAN XINGYI MED TECH CO LTD | 2016-05-04 | — | — | CN | disclosed |