Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 7/20 | 0.47 |
| ▸ | KIT | P10721 | 6/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.47 |
| ▸ | FLT4 | P35916 | 5/20 | 0.47 |
| ▸ | FLT3 | P36888 | 5/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | ACVRL1 | P37023 | 4/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.47 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314134 | 0.80 | OPRD1 (0.62) | KDM4EGAASMN1; SMN2OPRD1KDR | |
| SCHEMBL3366271 | 0.80 | OPRD1 (0.62) | KDM4EGAASMN1; SMN2OPRD1KDR | |
| SCHEMBL30330184 | 0.79 | CYP19A1 (0.50) | KDM4EGAASMN1; SMN2KDRKIT | |
| SCHEMBL28057641 | 0.79 | CYP19A1 (0.50) | KDM4EGAASMN1; SMN2KDRKIT | |
| SCHEMBL16430754 | 0.77 | CYP19A1 (0.64) | SMN1; SMN2CYP19A1ALDH1A1 | |
| SCHEMBL28721233 | 0.75 | CYP19A1 (0.56) | KDM4ESMN1; SMN2CYP19A1MKNK2ALDH1A1 | |
| SCHEMBL30801445 | 0.74 | CYP19A1 (0.66) | KDM4EGAASMN1; SMN2OPRD1KDR | |
| SCHEMBL28286221 | 0.70 | NPC1 (0.54) | — | |
| SCHEMBL2060277 | 0.70 | KDM4E (1.00) | KDM4EGAASMN1; SMN2OPRD1KDR | |
| SCHEMBL19476026 | 0.68 | KDM4E (0.63) | KDM4EGAASMN1; SMN2OPRD1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10674699-B2 | Endophyte enhanced seedlings with increased pest tolerance | Irving Licensing Inc. (CA) | 2020-06-09 | — | — | US | claimed |
| US-20170164621-A1 | ENDOPHYTE ENHANCED SEEDLINGS WITH INCREASED PEST TOLERANCE | Irving Licensing Inc. (CA) | 2017-06-15 | — | — | US | claimed |
| US-9549528-B2 | Endophyte enhanced seedlings with increased pest tolerance | J.D. IRVING LIMITED (CA) | 2017-01-24 | — | — | US | claimed |
| EP-2069499-B1 | ENDOPHYTE ENHANCED SEEDLINGS WITH INCREASED PEST TOLERANCE | J D IRVING LTD (CA) | 2016-12-14 | — | — | EP | claimed |
| US-20130219569-A1 | ENDOPHYTE ENHANCED SEEDLINGS WITH INCREASED PEST TOLERANCE | J.D. IRVING LIMITED (CA) | 2013-08-22 | — | — | US | claimed |
| US-20110173727-A1 | Endophyte Enhanced Seedlings with Increased Pest Tolerance | J.D. IRVING, LIMITED (CA) | 2011-07-14 | — | — | US | claimed |
| EP-2069499-A2 | ENDOPHYTE ENHANCED SEEDLINGS WITH INCREASED PEST TOLERANCE | J.D. Irving, Limited (CA) | 2009-06-17 | — | — | EP | claimed |
| WO-2008049209-A2 | ENDOPHYTE ENHANCED SEEDLINGS WITH INCREASED PEST TOLERANCE | J.D. IRVING, LIMITED (CA) | 2008-05-02 | — | — | WO | claimed |
| US-10674699-B2 | Endophyte enhanced seedlings with increased pest tolerance | Irving Licensing Inc. (CA) | 2020-06-09 | — | — | US | disclosed |
| US-20170164621-A1 | ENDOPHYTE ENHANCED SEEDLINGS WITH INCREASED PEST TOLERANCE | Irving Licensing Inc. (CA) | 2017-06-15 | — | — | US | disclosed |
| US-9549528-B2 | Endophyte enhanced seedlings with increased pest tolerance | J.D. IRVING LIMITED (CA) | 2017-01-24 | — | — | US | disclosed |
| EP-2069499-B1 | ENDOPHYTE ENHANCED SEEDLINGS WITH INCREASED PEST TOLERANCE | J D IRVING LTD (CA) | 2016-12-14 | — | — | EP | disclosed |
| US-20130219569-A1 | ENDOPHYTE ENHANCED SEEDLINGS WITH INCREASED PEST TOLERANCE | J.D. IRVING LIMITED (CA) | 2013-08-22 | — | — | US | disclosed |
| US-8455395-B2 | Endophyte enhanced seedlings with increased pest tolerance | IRVING LICENSING, INC. (CA) | 2013-06-04 | — | — | US | disclosed |
| US-20110173727-A1 | Endophyte Enhanced Seedlings with Increased Pest Tolerance | J.D. IRVING, LIMITED (CA) | 2011-07-14 | — | — | US | disclosed |
| EP-2069499-A2 | ENDOPHYTE ENHANCED SEEDLINGS WITH INCREASED PEST TOLERANCE | J.D. Irving, Limited (CA) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008049209-A2 | ENDOPHYTE ENHANCED SEEDLINGS WITH INCREASED PEST TOLERANCE | J.D. IRVING, LIMITED (CA) | 2008-05-02 | — | — | WO | disclosed |