Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTPRF | P10586 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14312130 | 0.77 | MAPT (0.50) | TDP1CA1CA2CA9ALDH1A1 | |
| SCHEMBL27983588 | 0.77 | CES2 (0.58) | KMT2ACA1CA2CA9ALDH1A1 | |
| SCHEMBL5169177 | 0.77 | KDM4E (0.56) | KMT2ATDP1CA1CA2CA9 | |
| SCHEMBL20543307 | 0.75 | MYC (0.48) | CA1CA2CA9ALDH1A1KDM4E | |
| SCHEMBL28053292 | 0.73 | ALDH1A1 (0.56) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL967996 | 0.73 | ALDH1A1 (0.56) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL8813905 | 0.73 | ALDH1A1 (0.56) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL1298701 | 0.72 | MEN1 (0.54) | MEN1KMT2ATDP1CA1CA2 | |
| SCHEMBL28516295 | 0.72 | NR4A1 (0.57) | MEN1KMT2ATDP1CA1CA2 | |
| SCHEMBL27476281 | 0.72 | PTGS1 (0.41) | CA1CA2CA9ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105531269-A | \"inhibitors of nicotinamide phosphoribosyltransferase, compositions, products and uses thereof\ | UNIV DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO | 2016-04-27 | — | — | CN | disclosed |