Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 8/20 | 0.38 |
| ▸ | MMP3 | P08254 | 5/20 | 0.38 |
| ▸ | MMP1 | P03956 | 5/20 | 0.38 |
| ▸ | ADAM9 | Q13443 | 3/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | AREG | P15514 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5740070 | 0.80 | MMP8 (0.43) | MMP2ANPEPMMP9MMP3MMP1 | |
| SCHEMBL3240479 | 0.80 | MMP9 (0.43) | MMP9MMP3MMP1ADAM9ADAM17 | |
| SCHEMBL6369530 | 0.79 | NR1D1 (0.45) | MMP9MMP3MMP1ADAM9ADAM17 | |
| SCHEMBL12125014 | 0.79 | NR1D1 (0.45) | MMP9MMP3MMP1ADAM9ADAM17 | |
| SCHEMBL6962464 | 0.78 | SLC6A4 (0.46) | — | |
| SCHEMBL7332043 | 0.76 | CYP19A1 (0.42) | MMP2ANPEPMMP9MMP3MMP1 | |
| SCHEMBL28057905 | 0.76 | NR1D1 (0.41) | MMP9MMP3MMP1ADAM9ADAM17 | |
| SCHEMBL12992250 | 0.74 | CHEK1 (0.46) | MMP2ANPEPMMP9MMP3MMP1 | |
| SCHEMBL13545530 | 0.74 | CHEK1 (0.46) | MMP2ANPEPMMP9MMP3MMP1 | |
| SCHEMBL29177033 | 0.72 | CHEK1 (0.47) | MMP2ANPEPMMP9MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101597196-B | Improved drug candidate and preparation method thereof | JIYAKETA CO., LTD. (CH) | 2016-05-04 | — | — | CN | disclosed |