Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28058016 | 0.86 | EPHX2 (0.44) | MEN1KMT2AEPHX2ALDH1A1NPSR1 | |
| SCHEMBL28058013 | 0.77 | EPHX2 (0.41) | EPHX2ALDH1A1 | |
| SCHEMBL10312482 | 0.71 | GRIN2D (0.54) | MEN1KMT2AEPHX2ALDH1A1TSHR | |
| SCHEMBL28222413 | 0.70 | KMT2A (0.61) | MEN1KMT2AEPHX2ALDH1A1TSHR | |
| SCHEMBL26687399 | 0.69 | KMT2A (0.64) | MEN1KMT2AEPHX2ALDH1A1NPSR1 | |
| SCHEMBL26687425 | 0.69 | MEN1 (0.59) | MEN1KMT2AEPHX2ALDH1A1TSHR | |
| SCHEMBL918262 | 0.69 | MEN1 (0.51) | MEN1KMT2AEPHX2ALDH1A1TSHR | |
| SCHEMBL25475060 | 0.67 | KMT2A (0.49) | MEN1KMT2AEPHX2ALDH1A1NPSR1 | |
| SCHEMBL9289043 | 0.67 | KMT2A (0.53) | MEN1KMT2AEPHX2ALDH1A1NPSR1 | |
| SCHEMBL21724708 | 0.67 | EPHX2 (0.50) | MEN1KMT2AEPHX2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101597196-B | Improved drug candidate and preparation method thereof | JIYAKETA CO., LTD. (CH) | 2016-05-04 | — | — | CN | disclosed |