SCHEMBL28058013

SCHEMBL28058013

O=[SH](=O)OCCCNC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 18/20 0.41
ALDH1A1 P00352 1/20 0.40
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27739998 0.79 GRIN1 (0.51) EPHX2
SCHEMBL28058028 0.77 MEN1 (0.47) EPHX2ALDH1A1
SCHEMBL1082075 0.77 EPHX2 (0.50) EPHX2HTT
SCHEMBL28058016 0.76 EPHX2 (0.44) EPHX2ALDH1A1
SCHEMBL19798760 0.74 EPHX2 (0.58) EPHX2HTT
SCHEMBL3188537 0.72 GRIN2D (0.50) EPHX2
SCHEMBL23934062 0.70 GRIN2D (0.48) EPHX2HTT
SCHEMBL11922812 0.70 EPHX2 (0.49) EPHX2
SCHEMBL28057903 0.69 LMNA (0.46) EPHX2ALDH1A1
SCHEMBL19798464 0.68 ALDH1A1 (0.57) EPHX2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101597196-B Improved drug candidate and preparation method thereof JIYAKETA CO., LTD. (CH) 2016-05-04 CN disclosed