Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27551919 | 0.98 | KMT2A (0.51) | KMT2AMEN1L3MBTL1EPHX2HSD17B10 | |
| SCHEMBL24842308 | 0.91 | KMT2A (0.43) | KMT2AMEN1L3MBTL1EPHX2HSD17B10 | |
| SCHEMBL28222413 | 0.86 | KMT2A (0.61) | KMT2AMEN1L3MBTL1EPHX2HSD17B10 | |
| SCHEMBL13069834 | 0.82 | KMT2A (0.47) | KMT2AMEN1EPHX2HSD17B10ALDH1A1 | |
| SCHEMBL1677910 | 0.81 | MEN1 (0.61) | KMT2AMEN1L3MBTL1EPHX2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27539754 | 0.79 | KMT2A (0.59) | KMT2AMEN1L3MBTL1EPHX2ALDH1A1 | |
| SCHEMBL21724708 | 0.78 | EPHX2 (0.50) | KMT2AMEN1EPHX2HSD17B10ALDH1A1 | |
| SCHEMBL25475060 | 0.78 | KMT2A (0.49) | KMT2AMEN1EPHX2HSD17B10ALDH1A1 | |
| SCHEMBL10312482 | 0.78 | GRIN2D (0.54) | KMT2AMEN1EPHX2HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1072535 | 0.77 | KMT2A (0.50) | KMT2AMEN1L3MBTL1EPHX2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127266-A1 | MALIC ENZYME INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2022-04-28 | — | — | US | disclosed |
| EP-2427425-B1 | TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS INC (US) | 2017-03-08 | — | — | EP | disclosed |
| CN-100522150-C | Angiogenesis inhibitor | SANTEN PHARMACEUTICAL CO LTD (JP) | 2009-08-05 | — | — | CN | disclosed |
| CN-1604774-A | Angiogenesis inhibitor | SANTEN PHARMACEUTICAL CO LTD (JP) | 2005-04-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127266-A1 | MALIC ENZYME INHIBITORS | ME1, ME2, ME3 | KMT2A 1797/4885MEN1 614/4885L3MBTL1 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.