Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | SERPINA2 | P20848 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30635450 | 0.79 | ATM (0.33) | BACE1KCNH2 | |
| SCHEMBL2712585 | 0.77 | CYP11B2 (0.46) | BACE1KCNH2PIK3CAPIK3CDPIK3CB | |
| SCHEMBL17686085 | 0.77 | PIK3CA (0.47) | BACE1KCNH2PIK3CAPIK3CDPIK3CB | |
| SCHEMBL29066296 | 0.77 | DYRK1A (0.39) | BACE1KCNH2PIK3CAPIK3CDPIK3CB | |
| SCHEMBL26560458 | 0.76 | HTR1D (0.43) | BACE1KCNH2PIK3CAPIK3CDPIK3CB | |
| SCHEMBL19209936 | 0.73 | DHFR (0.42) | BACE1KCNH2PIK3CAPIK3CDPIK3CB | |
| SCHEMBL18857842 | 0.72 | MAPK14 (0.47) | PIK3CAPIK3CDPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL31704858 | 0.72 | CYP11B2 (0.51) | PIK3CAPIK3CDPIK3CBPIK3CGCYP11B2 | |
| SCHEMBL31706135 | 0.72 | CYP11B2 (0.51) | PIK3CAPIK3CDPIK3CBPIK3CGCYP11B2 | |
| SCHEMBL2457641 | 0.72 | PIK3CA (0.41) | BACE1KCNH2PIK3CAPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104395297-B | Sulfonamide derivatives and pharmaceutical use thereof | AJINOMOTO CO.,INC. (JP) | 2016-05-04 | — | — | CN | disclosed |