Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR4 | O00206 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 3/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28058401 | 0.82 | ALDH1A1 (0.51) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL10717379 | 0.79 | ALDH1A1 (0.55) | KDM4EALDH1A1TLR4TLR2XDH | |
| SCHEMBL11103328 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1TLR4TLR2XDH | |
| SCHEMBL27781910 | 0.75 | KDM4E (0.50) | KDM4EALDH1A1TLR4TLR2XDH | |
| SCHEMBL2271210 | 0.75 | SMN1; SMN2 (0.54) | KDM4EALDH1A1TLR4TLR2XDH | |
| SCHEMBL1602832 | 0.75 | MAPK1 (0.51) | KDM4EALDH1A1TLR4TLR2XDH | |
| SCHEMBL476349 | 0.75 | ALDH1A1 (0.58) | KDM4EALDH1A1TLR4TLR2MEN1 | |
| SCHEMBL1128959 | 0.75 | VCAM1 (0.53) | KDM4EALDH1A1TLR4TLR2MEN1 | |
| SCHEMBL11692257 | 0.73 | TSHR (0.56) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11067702 | 0.73 | HTR6 (0.57) | KDM4EALDH1A1TLR4TLR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176192-A | ANTHELMINTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-11-27 | — | — | US | disclosed |