Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16045978 | 0.79 | ALDH1A1 (0.41) | HSD17B10CSF1RFGFR1FLT1KDR | |
| SCHEMBL16047469 | 0.79 | ALDH1A1 (0.46) | MAPTHSD17B10GSK3BCDK5CLK4 | |
| SCHEMBL16044197 | 0.78 | GABRA1 (0.38) | LMNAMAPK14KDM4C | |
| SCHEMBL16047603 | 0.78 | KDM4C (0.37) | CSF1RFGFR1FLT1KDRCSNK1A1 | |
| SCHEMBL16081993 | 0.77 | KDM4C (0.36) | CSF1RFGFR1FLT1KDRCSNK1A1 | |
| SCHEMBL16045254 | 0.76 | GRM1 (0.45) | MAPTHTTTP53LMNASMN1; SMN2 | |
| SCHEMBL16044246 | 0.75 | BRAF (0.39) | GSK3BHPGDMAPK14KDM4CMAPK1 | |
| SCHEMBL16045967 | 0.75 | TBXAS1 (0.34) | CSF1RFGFR1FLT1KDRCSNK1A1 | |
| SCHEMBL16045854 | 0.75 | BRAF (0.39) | GSK3BHPGDMAPK14KDM4CMAPK1 | |
| SCHEMBL18759455 | 0.74 | TP53 (0.33) | MAPTHSD17B10CSF1RFGFR1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105358561-A | Novel inhibitor compounds of phosphodiesterase type 10a | ABBVIE DEUTSCHLAND | 2016-02-24 | — | — | CN | disclosed |