Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931425 | 1.00 | CTSK (0.48) | CTSKCTSSITGB3ITGA2BTSHR | |
| SCHEMBL32681199 | 1.00 | CTSK (0.48) | CTSKCTSSITGB3ITGA2BTSHR | |
| SCHEMBL38660733 | 0.92 | CTSK (0.46) | CTSKCTSSITGB3ITGA2B | |
| SCHEMBL10656655 | 0.87 | CTSK (0.50) | CTSKCTSSITGB3ITGA2BHDAC4 | |
| SCHEMBL38662206 | 0.85 | CTSK (0.52) | CTSKCTSSITGB3ITGA2B | |
| SCHEMBL29576064 | 0.85 | BACE1 (0.52) | CTSKCTSSTSHR | |
| SCHEMBL20628143 | 0.85 | BACE1 (0.52) | CTSKCTSSTSHR | |
| SCHEMBL376450 | 0.84 | FOLH1 (0.53) | CTSKCTSSITGB3ITGA2BTSHR | |
| SCHEMBL47004 | 0.84 | FOLH1 (0.53) | CTSKCTSSITGB3ITGA2BTSHR | |
| SCHEMBL918952 | 0.84 | FOLH1 (0.53) | CTSKCTSSITGB3ITGA2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377848-A | Prodrug derivatives of substituted triazolopyridines | Bayer Pharma AG | 2016-03-02 | — | — | CN | disclosed |