Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.50 |
| ▸ | CTSS | P25774 | 5/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31206686 | 0.88 | ITGB3 (0.47) | CTSKCTSSITGB3ITGA2BHDAC4 | |
| SCHEMBL8931425 | 0.87 | CTSK (0.48) | CTSKCTSSITGB3ITGA2BHDAC4 | |
| SCHEMBL32681199 | 0.87 | CTSK (0.48) | CTSKCTSSITGB3ITGA2BHDAC4 | |
| SCHEMBL28058553 | 0.87 | CTSK (0.48) | CTSKCTSSITGB3ITGA2BHDAC4 | |
| SCHEMBL8183191 | 0.87 | MEN1 (0.57) | CTSKCTSSITGB3ITGA2BHDAC4 | |
| SCHEMBL16909076 | 0.87 | MEN1 (0.57) | CTSKCTSSITGB3ITGA2BHDAC4 | |
| SCHEMBL918952 | 0.86 | FOLH1 (0.53) | CTSKCTSSITGB3ITGA2BHDAC4 | |
| SCHEMBL47004 | 0.86 | FOLH1 (0.53) | CTSKCTSSITGB3ITGA2BHDAC4 | |
| SCHEMBL376450 | 0.86 | FOLH1 (0.53) | CTSKCTSSITGB3ITGA2BHDAC4 | |
| SCHEMBL9980623 | 0.85 | MEN1 (0.62) | CTSKCTSSHDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4742048-A | Tetrapeptides and pentapeptides, their preparation and compositions containing them | RHONE-POULENC INDUSTRIES (FR) | 1988-05-03 | — | — | US | disclosed |