Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.64 |
| ▸ | CTSS | P25774 | 2/20 | 0.64 |
| ▸ | CTSK | P43235 | 2/20 | 0.64 |
| ▸ | CTSB | P07858 | 1/20 | 0.64 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LAP3 | P28838 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66243 | 0.98 | CTSL (0.66) | CTSLCTSSCTSKCTSBCAPN1 | |
| SCHEMBL17559 | 0.98 | CTSL (0.66) | CTSLCTSSCTSKCTSBCAPN1 | |
| SCHEMBL17560 | 0.98 | CTSL (0.66) | CTSLCTSSCTSKCTSBCAPN1 | |
| Fluoride SCHEMBL27561259 | 0.97 | CTSL (0.64) | CTSLCTSSCTSKCTSBCAPN1 | |
| Water SCHEMBL11331808 | 0.97 | CTSS (0.68) | CTSLCTSSCTSKCTSBCAPN1 | |
| Water SCHEMBL1069558 | 0.97 | CTSS (0.68) | CTSLCTSSCTSKCTSBCAPN1 | |
| Water SCHEMBL2838131 | 0.97 | CTSS (0.68) | CTSLCTSSCTSKCTSBCAPN1 | |
| SCHEMBL8579795 | 0.97 | CTSL (0.64) | CTSLCTSSCTSKCTSBCAPN1 | |
| Water SCHEMBL645995 | 0.97 | CTSS (0.68) | CTSLCTSSCTSKCTSBCAPN1 | |
| Hydrazine SCHEMBL8410651 | 0.95 | CTSL (0.62) | CTSLCTSSCTSKCTSBCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377848-A | Prodrug derivatives of substituted triazolopyridines | Bayer Pharma AG | 2016-03-02 | — | — | CN | disclosed |