Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propofol SCHEMBL28550214 | 0.82 | GABRA1 (0.77) | GABRA1GABRB2GABRB1LMNACYP3A4 | |
| Propofol SCHEMBL28006278 | 0.80 | GABRA1 (0.74) | GABRA1GABRB2GABRB1LMNACYP3A4 | |
| Propofol SCHEMBL28796604 | 0.77 | GABRA1 (0.63) | GABRA1GABRB2GABRB1LMNACYP3A4 | |
| SCHEMBL28058764 | 0.76 | ALOX5 (0.44) | GABRA1GABRB2 | |
| Propofol SCHEMBL2414429 | 0.75 | GABRA1 (1.00) | GABRA1GABRB2GABRB1LMNACYP3A4 | |
| Propofol SCHEMBL36245 | 0.75 | GABRA1 (1.00) | GABRA1GABRB2GABRB1LMNACYP3A4 | |
| Propofol SCHEMBL10968613 | 0.73 | GABRA1 (0.94) | GABRA1GABRB2GABRB1LMNACYP3A4 | |
| Propofol SCHEMBL5036811 | 0.73 | GABRA1 (0.94) | GABRA1GABRB2GABRB1LMNACYP3A4 | |
| Propofol SCHEMBL1033835 | 0.73 | GABRA1 (0.94) | GABRA1GABRB2GABRB1LMNACYP3A4 | |
| Propofol SCHEMBL10968616 | 0.73 | GABRA1 (0.94) | GABRA1GABRB2GABRB1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104470985-B | The manufacture method of polymer composition and polymer composition | BRIDGESTONE CO.,LTD. (JP) | 2016-05-18 | — | — | CN | disclosed |
| CN-103154045-B | Copolymer and manufacture method thereof | BRIDGESTONE CO.,LTD. (JP) | 2016-05-11 | — | — | CN | disclosed |