Pyrimidine

Pyrimidine

SCHEMBL28058723

NNC(N)=O.c1cncnc1

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.53
TSHR P16473 2/20 0.53
NFKB1 P19838 2/20 0.53
MAOA P21397 1/20 0.53
MAOB P27338 1/20 0.53
THPO P40225 1/20 0.53
LMNA P02545 2/20 0.50
P2RX7 Q99572 4/20 0.42
CYP3A4 P08684 3/20 0.38
RECQL P46063 1/20 0.38
CYP2C9 P11712 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MPO P05164 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2A6 P11509 1/20 0.38
CYP2C19 P33261 1/20 0.38
F7 P08709 1/20 0.37
F3 P13726 1/20 0.37
SARM1 Q6SZW1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrimidine SCHEMBL28115899 0.84 TSHR (0.53) CYP1A2TSHRNFKB1MAOAMAOB
Pyridine SCHEMBL27474885 0.84 CYP1A2 (0.53) CYP1A2TSHRNFKB1MAOAMAOB
Pyrimidine SCHEMBL28421059 0.83 F7 (0.42) CYP1A2TSHRLMNAP2RX7CYP3A4
Pyrimidine SCHEMBL374258 0.83 F7 (0.42) CYP1A2TSHRLMNAP2RX7CYP3A4
Pyrimidine SCHEMBL27471792 0.82 RECQL (0.37) CYP1A2TSHRNFKB1MAOAMAOB
Pyrimidine SCHEMBL28845102 0.80 F7 (0.41) TSHRLMNAP2RX7RECQLADORA3
Pyrimidine SCHEMBL1150634 0.80 F7 (0.46) TSHRRECQLCYP2A6F7F3
Pyrimidine SCHEMBL28248566 0.80 F7 (0.41) TSHRLMNAP2RX7RECQLADORA3
Pyrimidine SCHEMBL28643613 0.80 F7 (0.46) TSHRRECQLCYP2A6F7F3
Pyrimidine SCHEMBL28251830 0.80 F7 (0.41) TSHRLMNAP2RX7RECQLADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110330688-B Special environment-friendly stabilizer for charging pile cable and preparation method thereof 盐城市朗创新材料有限公司 2021-10-29 CN claimed
CN-111073182-A Transparent composite PVC electric wire 新亚电子股份有限公司 2020-04-28 CN claimed
CN-110343037-A A kind of preparation method and application of high-performance heat stabilizer magnesium acetylacetonate 中山华明泰科技股份有限公司 2019-10-18 CN claimed
CN-110330688-A Dedicated stabilizer of charging pile cable and preparation method thereof 盐城市朗创新材料有限公司 2019-10-15 CN claimed
CN-110317418-A A kind of Environment-friendlyheat heat stabilizer and preparation method thereof for PVC hard product 盐城市朗创新材料有限公司 2019-10-11 CN claimed
CN-110283063-A A kind of preparation method and application of Acetylacetone lanthanum 中山华明泰科技股份有限公司 2019-09-27 CN claimed
CN-110041270-A A kind of preparation method of double semicarbazides pyrimidines in water phase 广州臻莱迈新材料科技有限公司 2019-07-23 CN claimed
CN-109401122-A A kind of food-grade recyclable plastics material 揭阳市腾晟科技咨询有限公司 2019-03-01 CN claimed
CN-109020899-A A kind of urea pyrimidine maleic amide acid polyol ester and its preparation method and application 广东工业大学 2018-12-18 CN claimed
CN-108384059-A A kind of calcium-zinc composite stabilizing agent and preparation method thereof 韩路易 2018-08-10 CN claimed
CN-108383800-A Semicarbazides pyrimidine maleic amide hydrochlorate and preparation method and polychloroethylene heat stabilizer 广东工业大学 2018-08-10 CN claimed
CN-108329275-A Semicarbazides pyrimidine maleamic acid and preparation method thereof and polychloroethylene heat stabilizer 广东工业大学 2018-07-27 CN claimed
CN-105802070-B A kind of method and its application that hydrocalumite base heat stabilizer is prepared by calcium aluminium hydroxide 江南大学 2018-02-06 CN claimed
CN-105778344-B A kind of solid PVC heat stabilizer rare earth modified by the acetylacetone,2,4-pentanedione that adulterates and its application 江南大学 2017-07-07 CN claimed
CN-106432963-A Preparation and application of special zinc cyanurate compound stabilizer for novel environment-friendly PVC (polyvinyl chloride) profiles 深圳市志海实业股份有限公司 2017-02-22 CN claimed
CN-105802070-A Method for preparing hydrocalumite based heat stabilizer from calcium-aluminum hydroxide and application of hydrocalumite based heat stabilizer 江南大学 2016-07-27 CN claimed
CN-105778344-A Solid PVC heat stabilizer modified through doping of acetylacetone rare earth and application of stabilizer 江南大学 2016-07-20 CN claimed
CN-110330688-B Special environment-friendly stabilizer for charging pile cable and preparation method thereof 盐城市朗创新材料有限公司 2021-10-29 CN disclosed
CN-105802070-A Method for preparing hydrocalumite based heat stabilizer from calcium-aluminum hydroxide and application of hydrocalumite based heat stabilizer 江南大学 2016-07-27 CN disclosed
CN-105778344-A Solid PVC heat stabilizer modified through doping of acetylacetone rare earth and application of stabilizer 江南大学 2016-07-20 CN disclosed