Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.52 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | FRK | P42685 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.49 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.49 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.49 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28059020 | 0.86 | AURKA (0.55) | MAPK14IKBKBMAPK13PRKD3MAP4K4 | |
| SCHEMBL28059099 | 0.85 | MAPK14 (0.48) | MAPK14IKBKBMAPK13PRKD3MAP4K4 | |
| SCHEMBL28059011 | 0.81 | ABCB1 (0.47) | MAPK14MAPK1MEN1KMT2APOLB | |
| SCHEMBL4259048 | 0.79 | MAPK14 (0.69) | MAPK14IKBKBMAPK13PRKD3MAP4K4 | |
| Hydrochloric Acid SCHEMBL4258929 | 0.78 | MAPK14 (0.68) | MAPK14IKBKBMAPK13PRKD3MAP4K4 | |
| SCHEMBL1520310 | 0.78 | NPC1 (0.65) | MEN1GAAKMT2APOLB | |
| SCHEMBL28059033 | 0.78 | SORT1 (0.44) | MAPK14IKBKBMAPK13PRKD3MAP4K4 | |
| SCHEMBL4257741 | 0.78 | MAPK14 (0.82) | MAPK14IKBKBMAPK13PRKD3MAP4K4 | |
| SCHEMBL28059002 | 0.77 | PIK3C3 (0.52) | MAPK14MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL28059009 | 0.75 | MEN1 (0.46) | MAPK1MAPK8MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105585565-A | 2-phenylamino-4-thiazolyl pyridine derivatives, preparing method thereof, pharmaceutical compositions of the derivatives and uses of the derivatives | INST MATERIA MEDICA CAMS | 2016-05-18 | — | — | CN | claimed |
| CN-105585565-A | 2-phenylamino-4-thiazolyl pyridine derivatives, preparing method thereof, pharmaceutical compositions of the derivatives and uses of the derivatives | INST MATERIA MEDICA CAMS | 2016-05-18 | — | — | CN | disclosed |