Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.43 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27936973 | 0.95 | RAB9A (0.43) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8770543 | 0.85 | RAB9A (0.45) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28797314 | 0.84 | MAPT (0.47) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL27937047 | 0.83 | PKM (0.44) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28805604 | 0.82 | HPGDS (0.48) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1664600 | 0.81 | RAB9A (0.61) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28059459 | 0.80 | PKM (0.61) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL27868382 | 0.78 | RAB9A (0.47) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL27918304 | 0.78 | F2 (0.46) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1664598 | 0.77 | RAB9A (0.59) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102656141-B | Micromolecular compound of simulation hemopoieticgrowth factor and uses thereof | LIGAND PHARMACEUTICALS INC. (US) | 2016-04-06 | — | — | CN | disclosed |
| CN-103282034-A | Use of hematopoietic growth factor mimetics | LIGAND PHARM INC | 2013-09-04 | — | — | CN | disclosed |