SCHEMBL28059233

SCHEMBL28059233

[CH2]CC(CC(N)C(C)=O)C(N)=O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 6/20 0.36
SLC1A1 P43005 6/20 0.36
SLC1A3 P43003 5/20 0.36
GRIK1 P39086 11/20 0.35
GRIK2 Q13002 11/20 0.35
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
SLC7A5 Q01650 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16155058 0.79 SLC1A2 (0.36) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL27571652 0.76 SLC1A3 (0.43) SLC1A2SLC1A3CA1CA2SLC7A5
SCHEMBL8583187 0.74
SCHEMBL7306532 0.74 CA1 (0.34) CA1CA2
SCHEMBL10641706 0.74 SLC7A5 (0.43) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL16155055 0.73 CA1 (0.40) SLC1A2SLC1A1SLC1A3GRIK1GRIK2
SCHEMBL7859689 0.70
SCHEMBL13828772 0.70 NOS2 (0.38) SLC7A5
SCHEMBL13828774 0.70 NOS2 (0.38) SLC7A5
SCHEMBL13829043 0.70 NOS2 (0.38) SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102656141-B Micromolecular compound of simulation hemopoieticgrowth factor and uses thereof LIGAND PHARMACEUTICALS INC. (US) 2016-04-06 CN disclosed