SCHEMBL7306532

SCHEMBL7306532

[CH2]CC(CC(C)C(N)=O)C(N)=O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27571652 0.84 SLC1A3 (0.43) CA1CA2
SCHEMBL11960690 0.79 CA2 (0.50) CA1CA2
SCHEMBL371457 0.78
SCHEMBL14617630 0.77 CA2 (0.48) CA1CA2
SCHEMBL9611232 0.77 GABRR1 (0.38) CA1CA2
SCHEMBL28059233 0.74 SLC1A2 (0.36) CA1CA2
SCHEMBL7859689 0.73
SCHEMBL15451687 0.72
SCHEMBL277545 0.72
SCHEMBL15984867 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0678503-B1 Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities NOVARTIS AG (CH) 1999-09-01 EP disclosed
EP-0678500-A1 Alpha-amino alkanoic acids and reduction products as intermediates in the preparation of renin inhibitors CIBA-GEIGY AG (CH) 1995-10-25 EP disclosed
EP-0678503-A1 Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities CIBA-GEIGY AG (CH) 1995-10-25 EP disclosed