Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 3/20 | 0.38 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | RARG | P13631 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740640 | 0.89 | HCAR3 (0.55) | RAPGEF4HCAR3HPGDHCAR2RXRA | |
| SCHEMBL16595470 | 0.76 | HCAR3 (0.42) | RAPGEF4HCAR3HPGDHCAR2RXRA | |
| SCHEMBL30233739 | 0.76 | TUBB4A (0.56) | RAPGEF4HCAR3RXRAKDM4E | |
| SCHEMBL103922 | 0.76 | TUBB4A (0.56) | RAPGEF4HCAR3RXRAKDM4E | |
| SCHEMBL26119911 | 0.75 | MAPK11 (0.53) | RAPGEF4HCAR3HPGDHCAR2KDM4E | |
| SCHEMBL17275595 | 0.75 | RAPGEF4 (0.45) | RAPGEF4HCAR3HPGDHCAR2RXRA | |
| SCHEMBL5066699 | 0.75 | KDM4E (0.51) | RAPGEF4KDM4EPLA2G4AGRIN2DGRIN2A | |
| SCHEMBL31335989 | 0.74 | RAPGEF4 (0.49) | RAPGEF4HCAR3HPGDHCAR2RXRA | |
| Hydrazine SCHEMBL1997343 | 0.73 | TUBB4A (0.54) | RAPGEF4HCAR3RXRAKDM4E | |
| SCHEMBL5066779 | 0.73 | NOTUM (0.56) | RAPGEF4HCAR3HPGDRXRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102656141-B | Micromolecular compound of simulation hemopoieticgrowth factor and uses thereof | LIGAND PHARMACEUTICALS INC. (US) | 2016-04-06 | — | — | CN | disclosed |