Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL28144623 | 0.97 | CYP1A2 (0.60) | CYP1A2HDAC3HDAC4HDAC1HDAC7 | |
| Naphthalene SCHEMBL16044499 | 0.89 | NR4A2 (0.61) | CYP1A2HDAC3HDAC4HDAC1HDAC7 | |
| Naphthalene SCHEMBL30124954 | 0.89 | NR4A2 (0.61) | CYP1A2HDAC3HDAC4HDAC1HDAC7 | |
| Sebacic Acid SCHEMBL28907869 | 0.89 | HDAC11 (0.57) | CYP1A2HDAC3HDAC4HDAC1HDAC7 | |
| Naphthalene SCHEMBL28148380 | 0.89 | AKR1B1 (0.67) | HDAC11MAPTSMN1; SMN2LMNATSHR | |
| Stearic Acid SCHEMBL29123159 | 0.87 | GPR84 (0.68) | CYP1A2HDAC11MAPTRXFP1LMNA | |
| Decanoic Acid SCHEMBL31619443 | 0.87 | GPR84 (0.68) | CYP1A2HDAC11MAPTRXFP1LMNA | |
| Stearic Acid SCHEMBL16632630 | 0.87 | GPR84 (0.68) | CYP1A2HDAC11MAPTRXFP1LMNA | |
| Naphthalene SCHEMBL6898872 | 0.87 | LMNA (0.68) | CYP1A2HDAC3HDAC4HDAC1HDAC7 | |
| Myristic Acid SCHEMBL29097493 | 0.87 | GPR84 (0.68) | CYP1A2HDAC11MAPTRXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103382234-B | Process for producing polypropylene | PETROCHINA COMPANY LIMITED (CN) | 2016-04-06 | — | — | CN | claimed |
| CN-113226642-A | Polishing pad | 株式会社可乐丽 | 2021-08-06 | — | — | CN | disclosed |
| CN-109678705-A | Two acid esters compound of naphthalene and preparation method thereof and application as lubricating oil | 宝鸡文理学院 | 2019-04-26 | — | — | CN | disclosed |
| CN-103382234-B | Process for producing polypropylene | PETROCHINA COMPANY LIMITED (CN) | 2016-04-06 | — | — | CN | disclosed |