Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | DCAF1 | Q9Y4B6 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27696872 | 0.81 | HSP90AA1 (0.62) | LMNAHPGDALDH1A1HTTHSD17B10 | |
| SCHEMBL28059598 | 0.81 | DCAF1 (0.58) | LMNAHPGDHTTHSD17B10NPC1 | |
| SCHEMBL29438454 | 0.81 | ALDH1A1 (0.54) | LMNAHPGDALDH1A1HTTHSD17B10 | |
| SCHEMBL3690385 | 0.76 | HPGD (0.77) | LMNAHPGDALDH1A1HTTHSD17B10 | |
| SCHEMBL1672584 | 0.74 | TDP1 (0.63) | POLBKDM4EDCAF1KDM5BOPRM1 | |
| SCHEMBL20156052 | 0.74 | TSHR (0.54) | HPGDALDH1A1HSD17B10KDM4ENPC1 | |
| SCHEMBL27849839 | 0.71 | DCAF1 (0.56) | DCAF1KDM5BCSF1R | |
| SCHEMBL11587152 | 0.71 | HPGD (0.70) | LMNAHPGDALDH1A1HTTHSD17B10 | |
| SCHEMBL20767374 | 0.71 | DCAF1 (0.49) | DCAF1KDM5BOPRM1OPRK1 | |
| SCHEMBL30758600 | 0.71 | HPGD (0.70) | LMNAHPGDALDH1A1HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418505-B | Pyrazol acid amide compounds and its preparation method and purposes | 浙江树人大学 | 2018-02-02 | — | — | CN | disclosed |
| CN-105418505-A | Pyrazole amides compound, preparation method therefor and application thereof | UNIV ZHEJIANG SHUREN | 2016-03-23 | — | — | CN | disclosed |