Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCAF1 | Q9Y4B6 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27696872 | 0.90 | HSP90AA1 (0.62) | DCAF1HSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL28059476 | 0.81 | LMNA (0.51) | DCAF1NPC1RAB9ACYP3A4MAPT | |
| SCHEMBL1672584 | 0.74 | TDP1 (0.63) | DCAF1KDM5BTDP1 | |
| SCHEMBL7058035 | 0.74 | RAB9A (0.79) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL20156052 | 0.74 | TSHR (0.54) | DCAF1NPC1RAB9ACYP3A4SMN1; SMN2 | |
| SCHEMBL2273998 | 0.73 | ACLY (0.55) | DCAF1HSP90AA1HSP90AB1KDM5BTDP1 | |
| SCHEMBL3684485 | 0.73 | HPGD (0.79) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL29519361 | 0.73 | HPGD (0.79) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL10489953 | 0.71 | ALDH1A1 (0.76) | NPC1RAB9ACYP3A4SMN1; SMN2MAPT | |
| SCHEMBL20767374 | 0.71 | DCAF1 (0.49) | DCAF1HSP90AA1HSP90AB1KDM5BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418505-B | Pyrazol acid amide compounds and its preparation method and purposes | 浙江树人大学 | 2018-02-02 | — | — | CN | disclosed |
| CN-105418505-A | Pyrazole amides compound, preparation method therefor and application thereof | UNIV ZHEJIANG SHUREN | 2016-03-23 | — | — | CN | disclosed |