SCHEMBL28059481

SCHEMBL28059481

C=CC(=O)OC(CC)Oc1ccc(C(=O)c2ccc(O)cc2O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.44
ALDH1A1 P00352 5/20 0.44
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
NPC1 O15118 4/20 0.44
TP53 P04637 3/20 0.44
MAPT P10636 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
USP2 O75604 1/20 0.43
GAA P10253 1/20 0.43
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
LSS P48449 2/20 0.42
LMNA P02545 2/20 0.41
MAPK1 P28482 2/20 0.41
CYP1A2 P05177 1/20 0.41
PGR P06401 1/20 0.41
CYP2D6 P10635 1/20 0.41
SLC6A2 P23975 1/20 0.41
PDE4A P27815 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28013522 0.93 CA12 (0.45) HPGDALDH1A1MEN1KMT2ANPC1
SCHEMBL4190225 0.90 HPGD (0.54) HPGDALDH1A1MEN1KMT2ANPC1
SCHEMBL28059399 0.84 LMNA (0.53) HPGDALDH1A1MEN1KMT2ANPC1
SCHEMBL22721246 0.80 ALDH1A1 (0.44) HPGDALDH1A1MEN1KMT2ANPC1
SCHEMBL11966995 0.78 MAPT (0.42) HPGDALDH1A1KMT2ANPC1MAPT
SCHEMBL11171980 0.78 KMT2A (0.53) ALDH1A1KMT2ANPC1TP53MAPT
SCHEMBL30374998 0.78 KMT2A (0.57) HPGDALDH1A1MEN1KMT2ANPC1
SCHEMBL5710117 0.78 KMT2A (0.57) HPGDALDH1A1MEN1KMT2ANPC1
SCHEMBL28244460 0.77 THRB (0.48) ALDH1A1KMT2ANPC1TP53MAPT
SCHEMBL14113638 0.76 MAPT (0.43) HPGDALDH1A1KMT2ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105802487-A Actinic energy radiation-curable acrylic silicone resin composition and coated article 信越化学工业株式会社 2016-07-27 CN disclosed