SCHEMBL28059620

SCHEMBL28059620

CCc1c(O)cccc1-c1ccccc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
BCL2L1 Q07817 1/20 0.43
DPP4 P27487 2/20 0.40
LMNA P02545 2/20 0.39
TSHR P16473 2/20 0.39
PPIA P62937 1/20 0.39
CASR P41180 2/20 0.38
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
CA12 O43570 2/20 0.38
CA2 P00918 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CA14 Q9ULX7 2/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
GMNN O75496 1/20 0.38
EGFR P00533 1/20 0.38
FYN P06241 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16527875 0.93 GABRA1 (0.42) ALDH1A1HPGDHSD17B10BCL2L1DPP4
SCHEMBL10679098 0.86 GABRA1 (0.48) DPP4TSHRCASRGABRA1GABRB2
SCHEMBL983104 0.86 GABRA1 (0.48) ALDH1A1HPGDHSD17B10BCL2L1DPP4
SCHEMBL2683682 0.83 ALDH1A1 (0.56) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
SCHEMBL10424340 0.83 GCGR (0.46) ALDH1A1HPGDHSD17B10BCL2L1DPP4
SCHEMBL31243574 0.83 TRPA1 (0.45) ALDH1A1HPGDHSD17B10DPP4LMNA
SCHEMBL323997 0.82 ALDH1A1 (0.54) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
Ammonia Solution, Strong SCHEMBL324959 0.82 ALDH1A1 (0.54) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
Water SCHEMBL28266485 0.82 ALDH1A1 (0.54) ALDH1A1HPGDHSD17B10BCL2L1SMN1; SMN2
SCHEMBL31243572 0.81 TRPA1 (0.41) ALDH1A1HPGDHSD17B10LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102105439-B Method for producing N-substituted carbamate and method for producing isocyanate using the N-substituted carbamate ASAHI KASEI CHEMICALS CORP. (JP) 2016-04-20 CN disclosed