Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2152013 | 0.79 | — | — | |
| SCHEMBL3828122 | 0.79 | — | — | |
| SCHEMBL1572232 | 0.77 | — | — | |
| SCHEMBL31336777 | 0.77 | — | — | |
| SCHEMBL11807989 | 0.74 | ADH1B (0.39) | ADH1BADH1CADH1A | |
| SCHEMBL11706931 | 0.64 | ALDH1A1 (0.42) | MEN1KMT2A | |
| SCHEMBL10907928 | 0.62 | ALDH1A1 (0.43) | KMT2A | |
| Phosphine SCHEMBL1716795 | 0.62 | — | — | |
| SCHEMBL11575400 | 0.61 | KEAP1 (0.42) | MEN1KMT2A | |
| SCHEMBL4639528 | 0.60 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103724279-B | One step to form the loop prepares the convenient synthetic method of 2-methyl-4-amino-5-amino methylpyrimidine | XINFA PHARMACEUTICAL CO., LTD. (CN) | 2016-04-06 | — | — | CN | disclosed |