Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28059710 | 0.81 | KMT2A (0.48) | ERN1KDM4EMAPTHSD17B10GAA | |
| SCHEMBL6929061 | 0.79 | TSHR (0.46) | KDM4EHTTMAPTHSD17B10GAA | |
| SCHEMBL8817298 | 0.78 | ERN1 (0.61) | ERN1KDM4EHTTPKMLMNA | |
| SCHEMBL4172887 | 0.72 | LMNA (0.54) | KDM4EHTTMAPTHSD17B10PKM | |
| SCHEMBL29393896 | 0.71 | HTT (0.44) | KDM4EHTTMAPTHSD17B10GAA | |
| SCHEMBL340402 | 0.70 | CYP1A2 (0.63) | KDM4EHTTHSD17B10LMNAALDH1A1 | |
| SCHEMBL29728547 | 0.70 | NCEH1 (0.47) | KDM4EHTTMAPTHSD17B10GAA | |
| SCHEMBL3953630 | 0.70 | LMNA (0.52) | HTTMAPTHSD17B10GAAPKM | |
| SCHEMBL31277250 | 0.70 | LMNA (0.52) | HTTMAPTHSD17B10PKMLMNA | |
| SCHEMBL3262903 | 0.70 | LMNA (0.52) | HTTMAPTHSD17B10PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560898-B1 | PHOTOCHROMIC NAPHTHOPYRANS | PPG INDUSTRIES INC (US) | 1997-03-26 | — | — | EP | disclosed |
| US-5340857-A | Ophthalmic lenses, plastic transparencies | PPG INDUSTRIES, INC. (US) | 1994-08-23 | — | — | US | disclosed |
| EP-0560898-A4 | PHOTOCHROMIC NAPHTHOPYRANS | — | 1993-11-18 | — | — | EP | disclosed |
| EP-0560898-A1 | PHOTOCHROMIC NAPHTHOPYRANS. | PPG INDUSTRIES INC (US) | 1993-09-22 | — | — | EP | disclosed |
| US-5244602-A | Photochromic articles comprising polymerized organic host material and naphthopyran | PPG INDUSTRIES, INC. (US) | 1993-09-14 | — | — | US | disclosed |
| WO-1992009593-A1 | PHOTOCHROMIC NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1992-06-11 | — | — | WO | disclosed |