Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | AKT2 | P31751 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295195 | 0.86 | CDC7 (0.53) | L3MBTL1CDC7CDK2CYP2C19RAPGEF4 | |
| SCHEMBL16863761 | 0.85 | RAPGEF4 (0.50) | L3MBTL1CDC7CDK2CYP2C19CYP1A2 | |
| SCHEMBL1150333 | 0.84 | CDC7 (0.54) | L3MBTL1CDC7CDK2CYP2C19BRAF | |
| SCHEMBL30828406 | 0.84 | CDC7 (0.54) | L3MBTL1CDC7CDK2CYP2C19BRAF | |
| SCHEMBL7892111 | 0.83 | CDC7 (0.50) | CDC7CDK2CYP2C19HPGDBRAF | |
| SCHEMBL20603929 | 0.83 | CDC7 (0.58) | L3MBTL1CDC7CDK2CYP2C19AKT1 | |
| SCHEMBL28547121 | 0.83 | CDC7 (0.50) | L3MBTL1CDC7CDK2CYP2C19CYP1A2 | |
| SCHEMBL27839782 | 0.83 | BIRC5 (0.54) | CDC7CDK2CYP2C19HPGDENPP3 | |
| SCHEMBL28545830 | 0.82 | BRAF (0.47) | CDC7CDK2BRAFALDH1A1SLC22A12 | |
| SCHEMBL20627651 | 0.82 | CDC7 (0.47) | L3MBTL1CDC7CDK2CYP2C19ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480111-A | Synthesis method of 7-azaindole substituted aryl acetate compound | 江苏理工学院 | 2021-03-12 | — | — | CN | disclosed |