Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6039784 | 0.98 | HPGD (0.46) | HPGDPREPSMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL6039893 | 0.94 | HPGD (0.42) | HPGDPREPSMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL13533886 | 0.82 | USP2 (0.56) | HPGDSMN1; SMN2USP2ALDH1A1EPHX1 | |
| SCHEMBL2264197 | 0.80 | CA2 (0.41) | HPGDSMN1; SMN2USP2CA1CA2 | |
| SCHEMBL19852529 | 0.78 | HPGD (0.71) | HPGDPREPSMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL60470 | 0.78 | HPGD (0.71) | HPGDPREPSMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL18097955 | 0.78 | HPGD (0.71) | HPGDPREPSMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL2077166 | 0.78 | HPGD (0.71) | HPGDPREPSMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL18432213 | 0.78 | HPGD (0.71) | HPGDPREPSMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL21707988 | 0.78 | HPGD (0.71) | HPGDPREPSMN1; SMN2USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105821013-B | Carbonyl reductase and its application in the chiral N-protected-hydroxyl azacyclo- of preparation | 华东理工大学 | 2019-05-03 | — | — | CN | disclosed |
| CN-106631992-A | Synthesis method of 4-oxy-3,4-dihydro-2H-pyridine-1-tert-butyl formate | 桑迪亚医药技术（上海）有限责任公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-105821013-A | Carbonyl reductase and application thereof in preparation of Chiral N-protecting-hydroxy nitrogen heterocycle | 华东理工大学 | 2016-08-03 | — | — | CN | disclosed |