Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6039784 | 0.96 | HPGD (0.46) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL13533886 | 0.83 | USP2 (0.56) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL2264197 | 0.82 | CA2 (0.41) | HPGDSMN1; SMN2USP2CA1CA2 | |
| SCHEMBL4081702 | 0.81 | HPGD (0.41) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL861278 | 0.77 | USP2 (0.64) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL15050742 | 0.76 | ALDH1A1 (0.48) | HPGDSMN1; SMN2MEN1KMT2AEPHX1 | |
| Iodide SCHEMBL15174787 | 0.76 | USP2 (0.62) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL16612394 | 0.76 | USP2 (0.62) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL9353116 | 0.75 | GAA (0.42) | HPGDSMN1; SMN2KMT2AMAPTALDH1A1 | |
| SCHEMBL7416322 | 0.74 | USP2 (0.55) | HPGDSMN1; SMN2USP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |