Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2191691 | 0.76 | CA14 (0.40) | ACHE | |
| SCHEMBL6946858 | 0.75 | ACHE (0.46) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28251151 | 0.75 | CHRM2 (0.35) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL6837623 | 0.74 | ACHE (0.44) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL24587789 | 0.73 | ACHE (0.52) | ACHE | |
| SCHEMBL27896304 | 0.73 | CHRM2 (0.33) | CHRNB2CHRNA4 | |
| SCHEMBL4654311 | 0.73 | ACHE (0.43) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL8741737 | 0.71 | TDP1 (0.43) | ACHE | |
| SCHEMBL25488667 | 0.70 | ACHE (0.50) | ACHE | |
| SCHEMBL28060047 | 0.68 | CHRNB2 (0.32) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102821602-B | Fatty Acid Fumarate Derivative and uses thereof | CATABASIS PHARMACEUTICALS, INC. (US) | 2016-04-20 | — | — | CN | disclosed |