Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28739361 | 0.83 | OPRM1 (0.32) | — | |
| SCHEMBL28739293 | 0.83 | — | — | |
| SCHEMBL7778990 | 0.78 | FABP3 (0.37) | GABRA1HTR2CHTR2BGABRB2 | |
| SCHEMBL7778968 | 0.77 | BRD4 (0.38) | MAPTCA1CA2CYP1A2HPGD | |
| SCHEMBL28940452 | 0.76 | MAPT (0.47) | MAPTGABRA1GABRG2GABRB3FAAH | |
| SCHEMBL7778979 | 0.75 | HTR2B (0.38) | HTR2B | |
| SCHEMBL14031957 | 0.73 | GABRA1 (0.39) | MAPTGABRA1GABRG2GABRB3FAAH | |
| SCHEMBL14501892 | 0.72 | BRD4 (0.35) | LMNA | |
| SCHEMBL14501893 | 0.71 | MAPT (0.32) | MAPTRECQL | |
| SCHEMBL7783990 | 0.69 | KDM4E (0.38) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063254-A1 | PHENOL DERIVATIVE AND APPLICATION THEREOF IN MEDICINE | 天地恒一制药股份有限公司 | 2022-03-31 | — | — | WO | disclosed |
| CN-114249652-A | Phenol derivative and application thereof in medicine | 天地恒一制药股份有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-105384608-B | A kind of cumene amphyl and preparation method thereof | 四川海思科制药有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-105384608-A | Isopropyl-phenol derivative and preparation method therefor | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2016-03-09 | — | — | CN | disclosed |