Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14501899 | 0.81 | — | — | |
| SCHEMBL14501893 | 0.79 | MAPT (0.32) | BRD4 | |
| SCHEMBL28060084 | 0.72 | MAPT (0.36) | LMNA | |
| SCHEMBL9261653 | 0.64 | GABRA1 (0.39) | BRD4LMNASOAT1 | |
| SCHEMBL28940452 | 0.64 | MAPT (0.47) | LMNAKMT2A | |
| SCHEMBL14031957 | 0.61 | GABRA1 (0.39) | LMNA | |
| SCHEMBL7164445 | 0.60 | ALDH1A1 (0.49) | KMT2A | |
| SCHEMBL28739361 | 0.59 | OPRM1 (0.32) | — | |
| SCHEMBL28739293 | 0.59 | — | — | |
| SCHEMBL16844493 | 0.57 | LMNA (0.33) | LMNAKMT2ASOAT1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220875-B2 | Amino acid derived prodrugs of propofol, compositions and uses thereof | XENOPORT, INC. | 2007-05-22 | — | — | US | disclosed |