Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.57 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.57 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | GSK3A | P49840 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.57 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.57 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28060192 | 0.77 | MEN1 (1.00) | MAPTMEN1GAAKMT2ANPSR1 | |
| SCHEMBL1208092 | 0.74 | SNCA (0.84) | MAPTMEN1KMT2ASNCANOX1 | |
| SCHEMBL29625234 | 0.74 | SNCA (0.84) | MAPTMEN1KMT2ASNCANOX1 | |
| Dimethyl Sulfoxide SCHEMBL18398818 | 0.71 | SNCA (0.72) | MAPTMEN1KMT2ASNCANOX1 | |
| SCHEMBL26017582 | 0.70 | SNCA (0.70) | MAPTMEN1GAAKMT2ASNCA | |
| SCHEMBL29214094 | 0.69 | SNCA (0.79) | MAPTMEN1GAAKMT2ANPSR1 | |
| SCHEMBL30867073 | 0.69 | SNCA (0.79) | MAPTMEN1GAAKMT2ANPSR1 | |
| SCHEMBL239724 | 0.68 | SNCA (1.00) | MAPTMEN1GAAKMT2ANPSR1 | |
| SCHEMBL30769632 | 0.68 | SNCA (1.00) | MAPTMEN1GAAKMT2ANPSR1 | |
| SCHEMBL499574 | 0.68 | MAOA (0.57) | MAPTSNCANOX1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503773-A | Preparation method of benzothiazine derivatives | UNIV SOOCHOW | 2016-04-20 | — | — | CN | disclosed |