Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 4/20 | 0.59 |
| ▸ | CES1 | P23141 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27912406 | 0.89 | HPGD (0.65) | KMT2APARP10HPGDMEN1MAPT | |
| SCHEMBL104891 | 0.84 | P2RX3 (0.54) | KMT2APARP10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9702616 | 0.82 | P2RX3 (0.53) | KMT2APARP10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17423634 | 0.81 | KMT2A (0.71) | KMT2APARP10CES2CES1HPGD | |
| SCHEMBL1029780 | 0.79 | KMT2A (0.68) | KMT2APARP10HPGDMEN1MAPT | |
| SCHEMBL13480847 | 0.78 | MAOB (0.72) | MAPTABCG2RAB9A | |
| SCHEMBL22967688 | 0.78 | MAOA (0.52) | KMT2APARP10CYP3A4HTR2APPARG | |
| SCHEMBL2517350 | 0.78 | KMT2A (0.73) | KMT2APARP10HPGDMEN1MAPT | |
| SCHEMBL4104645 | 0.77 | CNR1 (0.68) | KMT2AMEN1MAPTHTTSMN1; SMN2 | |
| SCHEMBL273857 | 0.77 | CES2 (1.00) | CES2CES1MAPTLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105769807-B | Pharmaceutical composition containing choline fenofibrate | 长春海悦药业股份有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-105769807-A | Pharmaceutical composition containing choline fenofibrate | 长春海悦药业股份有限公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-105581989-A | Pharmaceutical composition containing fenofibric acid | CHANGCHUN FUCHUN PHARMACEUTICAL CO LTD | 2016-05-18 | — | — | CN | disclosed |