Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28061249 | 0.81 | MAPT (0.38) | TDP1PDE4DNPC1MAPTNFKB1 | |
| SCHEMBL17979413 | 0.78 | GAA (0.32) | PDE4DNPC1MAPTNFKB1RAB9A | |
| SCHEMBL20642463 | 0.78 | ALDH1A1 (0.36) | PDE4DMAPTKCNH2DHFRLRRK2 | |
| SCHEMBL31575969 | 0.78 | L3MBTL1 (0.33) | PDE4DNPC1MAPTNFKB1RAB9A | |
| SCHEMBL29695090 | 0.78 | GAA (0.32) | PDE4DNPC1MAPTNFKB1RAB9A | |
| SCHEMBL29739284 | 0.76 | GRIN2B (0.38) | AAK1PDE4DNPC1MAPTNFKB1 | |
| SCHEMBL16641778 | 0.75 | GAA (0.50) | TDP1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL31493106 | 0.74 | KDM4E (0.36) | TDP1MAPTDHFRENPP1 | |
| SCHEMBL16783059 | 0.74 | RXRA (0.34) | PDE4DNPC1MAPTNFKB1RAB9A | |
| SCHEMBL26598715 | 0.74 | GAA (0.32) | PDE4DNPC1MAPTNFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103763923-B | 3-alkoxy-4-amino-6- (substituted) picolinates, 3-thioalkyl-4-amino-6- (substituted) picolinates, and 3-amino-4-amino-6- (substituted) picolinates and their use as herbicides | 陶氏益农公司 | 2016-08-17 | — | — | CN | disclosed |