Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL123189 | 0.83 | CHRNB2 (0.44) | CYP1A2CHRNB2SLC6A2CHRNB4CHRNA3 | |
| SCHEMBL5855213 | 0.83 | CHRNB2 (0.44) | CYP1A2CHRNB2SLC6A2CHRNB4CHRNA3 | |
| SCHEMBL11938179 | 0.83 | CHRNB2 (0.44) | CYP1A2CHRNB2SLC6A2CHRNB4CHRNA3 | |
| SCHEMBL10643075 | 0.82 | CHRNB2 (0.39) | CYP1A2CHRNB2SLC6A2CHRNB4CHRNA3 | |
| SCHEMBL2478984 | 0.75 | HTR1A (0.44) | HTR1AADRA1DCHRM2CHRM4CHRM1 | |
| SCHEMBL9608820 | 0.73 | HSD11B1 (0.40) | CYP1A2HSD11B1TSHROPRM1OPRK1 | |
| SCHEMBL1414768 | 0.73 | HTR1A (0.43) | HTR1AADRA1DCHRM2CHRM4CHRM1 | |
| SCHEMBL28216267 | 0.72 | HTR1A (0.39) | HTR1AADRA1DBACE1 | |
| SCHEMBL2382380 | 0.72 | HTR1A (0.39) | HTR1AADRA1DCYP1A2CHRNB2SLC6A2 | |
| SCHEMBL11465523 | 0.72 | HSD11B1 (0.39) | CYP1A2SLC6A2SLC6A3HSD11B1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103113400-B | The method of synthesis of phenyl methyl dioxane TMOS | Tianjin Kaimeitai Biological Science & Technology Co., Ltd. (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-103113400-B | The method of synthesis of phenyl methyl dioxane TMOS | Tianjin Kaimeitai Biological Science & Technology Co., Ltd. (CN) | 2016-04-27 | — | — | CN | disclosed |
| CN-103113400-B | The method of synthesis of phenyl methyl dioxane TMOS | Tianjin Kaimeitai Biological Science & Technology Co., Ltd. (CN) | 2016-04-27 | — | — | CN | disclosed |
| CN-103113400-B | The method of synthesis of phenyl methyl dioxane TMOS | Tianjin Kaimeitai Biological Science & Technology Co., Ltd. (CN) | 2016-04-27 | — | — | CN | disclosed |
| CN-101343285-B | Methyl-phenyl hybrid ring siloxane preparing method | UNIV HANGZHOU NORMAL | 2011-01-19 | — | — | CN | disclosed |
| CN-101343285-A | Methyl-phenyl hybrid ring siloxane preparing method | UNIV HANGZHOU NORMAL (CN) | 2009-01-14 | — | — | CN | disclosed |