SCHEMBL280615

SCHEMBL280615

CC(=O)Oc1ccc(C)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 1.00
MAPT P10636 3/20 0.59
POLB P06746 2/20 0.59
PKM P14618 1/20 0.59
ELANE P08246 1/20 0.57
HSD17B10 Q99714 1/20 0.55
ALDH1A1 P00352 4/20 0.54
GAA P10253 2/20 0.53
HSP90AA1 P07900 1/20 0.53
KMT2A Q03164 4/20 0.52
MEN1 O00255 2/20 0.52
KDM4E B2RXH2 1/20 0.52
TTR P02766 1/20 0.52
TP53 P04637 1/20 0.52
CYP3A4 P08684 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
GLA P06280 1/20 0.50
ACHE P22303 1/20 0.50
ESR1 P03372 1/20 0.48
PGR P06401 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3364633 0.98 LMNA (0.95) LMNAMAPTPOLBPKMELANE
SCHEMBL27835857 0.98 LMNA (0.95) LMNAMAPTPOLBPKMELANE
Ammonia Solution, Strong SCHEMBL27903026 0.98 LMNA (0.95) LMNAMAPTPOLBPKMELANE
SCHEMBL11056886 0.98 LMNA (0.95) LMNAMAPTPOLBPKMELANE
Hydrogen Sulfide SCHEMBL27637439 0.98 LMNA (0.95) LMNAMAPTPOLBPKMELANE
Phosphine SCHEMBL27576228 0.98 LMNA (0.95) LMNAMAPTPOLBPKMELANE
SCHEMBL19689201 0.98 LMNA (0.95) LMNAMAPTPOLBPKMELANE
SCHEMBL7798435 0.98 LMNA (0.95) LMNAMAPTPOLBPKMELANE
SCHEMBL27633104 0.98 LMNA (0.95) LMNAMAPTPOLBPKMELANE
Water SCHEMBL28334142 0.95 LMNA (0.91) LMNAMAPTPOLBPKMELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2875 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559703-B2 Fragrance composition GIVAUDAN SA (CH) 2026-02-24 US claimed
US-12498371-B2 Formulation for total and differential counting of leukocytes in liquid medium and method of making and using same HI TECHNOLOGIES LTDA (BR) 2025-12-16 US claimed
US-20250344991-A1 COMPOSITIONS AND METHODS FOR A UNIVERSAL CLINICAL TEST FOR OLFACTORY DYSFUNCTION UNIV ROCKEFELLER (US) 2025-11-13 US claimed
EP-4635407-A2 COMPOSITIONS AND METHODS FOR A UNIVERSAL CLINICAL TEST FOR OLFACTORY DYSFUNCTION The Rockefeller University (US) 2025-10-22 EP claimed
US-20250302678-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2025-10-02 US claimed
EP-3648613-B1 COMPOSITIONS AND METHODS FOR A UNIVERSAL CLINICAL TEST FOR OLFACTORY DYSFUNCTION UNIV ROCKEFELLER (US) 2025-09-24 EP claimed
US-12421475-B2 High performing, high impact bloom accord with a top, medium, and base note mixture INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-09-23 US claimed
US-12350136-B2 Absorbent articles including perfume and cyclodextrins THE PROCTER & GAMBLE COMPANY (US) 2025-07-08 US claimed
CN-119569711-A Double-targeting near-infrared ratio fluorescent probe and application thereof in preparation of carboxylesterase detection reagent 安徽大学 2025-03-07 CN claimed
EP-4514477-A1 FRAGRANCE COMPOSITIONS HAVING LONG-LASTING TRAIL PERFORMANCE Firmenich SA (CH) 2025-03-05 EP claimed
EP-0066864-A2 New chewing gum base and their use in a chewing gum NABISCO BRANDS, Inc. (US) 1982-12-15 EP claimed
US-4342877-A Process for the preparation of α-halogenated cresol esters EASTMAN KODAK COMPANY (US) 1982-08-03 US claimed
US-4335263-A MANY STEPS, STARTING WITH ACETYLATION OF M-CRESOL OR P-CRESOL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-06-15 US claimed
EP-0000932-B1 PRODUCTION OF N-ACYL-THIENAMYCINS MERCK & CO. INC. (US) 1981-10-21 EP claimed
US-4237309-A OXIDATION OF METHYL BENZENES IN THE PRESENCE OF ACETIC ANHYDRIDE AND BENZALDEHYDE AND AN ACID CATALYST SUNTECH, INC. (US) 1980-12-02 US claimed
US-4237310-A Co-oxidation of methyl benzenes and benzaldehyde to phenolics and formaldehyde SUNTECH, INC. (US) 1980-12-02 US claimed
US-4227012-A FORMS PHENOLIC ACETATES, PHOSPHORUS PENTOXIDE, BENZALDEHYDE CATALYSTS SUNTECH, INC. (US) 1980-10-07 US claimed
US-4212989-A ARYL ESTER SOLVENTS USED IN CATALYTIC CARBONYLATION FO ALCOHOLS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1980-07-15 US claimed
EP-0000932-A1 Production of N-acyl-thienamycins MERCK & CO. INC. (US) 1979-03-07 EP claimed
US-4135978-A PRODUCTION OF N-ACYL-THIENAMYCINS MERCK & CO., INC. (US) 1979-01-23 US claimed