SCHEMBL7798435

SCHEMBL7798435

CC(=O)Oc1ccc(C)cc1.[KH]

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.95
MAPT P10636 3/20 0.57
POLB P06746 2/20 0.57
PKM P14618 1/20 0.57
ELANE P08246 1/20 0.55
HSD17B10 Q99714 1/20 0.53
ALDH1A1 P00352 4/20 0.53
GAA P10253 2/20 0.52
HSP90AA1 P07900 1/20 0.52
KMT2A Q03164 4/20 0.50
MEN1 O00255 2/20 0.50
KDM4E B2RXH2 1/20 0.50
TTR P02766 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
GLA P06280 1/20 0.48
ACHE P22303 1/20 0.48
ESR1 P03372 1/20 0.47
PGR P06401 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL280615 0.98 LMNA (1.00) LMNAMAPTPOLBPKMELANE
SCHEMBL3364633 0.95 LMNA (0.95) LMNAMAPTPOLBPKMELANE
SCHEMBL27633104 0.95 LMNA (0.95) LMNAMAPTPOLBPKMELANE
SCHEMBL11056886 0.95 LMNA (0.95) LMNAMAPTPOLBPKMELANE
Phosphine SCHEMBL27576228 0.95 LMNA (0.95) LMNAMAPTPOLBPKMELANE
Ammonia Solution, Strong SCHEMBL27903026 0.95 LMNA (0.95) LMNAMAPTPOLBPKMELANE
SCHEMBL19689201 0.95 LMNA (0.95) LMNAMAPTPOLBPKMELANE
Hydrogen Sulfide SCHEMBL27637439 0.95 LMNA (0.95) LMNAMAPTPOLBPKMELANE
SCHEMBL27835857 0.95 LMNA (0.95) LMNAMAPTPOLBPKMELANE
Acetic Acid SCHEMBL11492381 0.93 LMNA (0.91) LMNAMAPTPOLBPKMELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100349979-C Polyphenylene sulfide resin compositions TORAY INDUSTRIES (JP) 2007-11-21 CN disclosed
CN-1798808-A Polyphenylene sulfide resin compositions TORAY INDUSTRIES (JP) 2006-07-05 CN disclosed
CN-1261488-C Process for producing polyarylene sulfide PHILLIPS PETROLEUM CO (US) 2006-06-28 CN disclosed
CN-1166699-C Recovery of modifier compounds and polar organic compounds from a poly (arylene sulfide) 2004-09-15 CN disclosed
CN-1159350-C Methanol extraction of polar organic compounds and modifier compounds from polyarylene sulfide polymer and oligomer streams 2004-07-28 CN disclosed
CN-1377376-A Recovery of modifier compounds and polar organic compounds from a poly (arylene sulfide) PHILLIPS PETROLEUM CO (US) 2002-10-30 CN disclosed
CN-1377381-A Process for producing polyarylene sulfide PHILLIPS PETROLEUM CO (US) 2002-10-30 CN disclosed
CN-1377375-A Methanol extraction polar organic compounds and modifier compounds from poly (arylene sulfide) polymer and oligomer streams PHILLIPS PETROLEUM CO (US) 2002-10-30 CN disclosed
EP-0594191-B1 Process for the removal of lower molecular weight fractions of poly(arylene sulfide) polymers PHILLIPS PETROLEUM CO (US) 2001-12-12 EP disclosed
US-5393865-A Poly(arylene sulfide) fibrid particles and process for their preparation PHILLIPS PETROLEUM COMPANY (US) 1995-02-28 US disclosed
US-5334701-A Extraction PHILLIPS PETROLEUM COMPANY (US) 1994-08-02 US disclosed
EP-0594191-A1 Process for the removal of lower molecular weight fractions of poly(arylene sulfide) polymers PHILLIPS PETROLEUM COMPANY (US) 1994-04-27 EP disclosed
EP-0534359-A1 Process for preparing arylene sulfide polymers PHILLIPS PETROLEUM COMPANY (US) 1993-03-31 EP disclosed
US-5166446-A PROCESS FOR THE PREPARATION OF POLYARYLENE SULFIDE HAVING A LOW ALKALIMETAL CONTENT AKZO N.V. (NL) 1992-11-24 US disclosed
EP-0468559-A1 Process for the preparation of polyarlene sulphide having a low alkali metal content Akzo Nobel N.V. (NL) 1992-01-29 EP disclosed
EP-0443509-A2 Process for preparing poly(arylene sulfide sulfone) PHILLIPS PETROLEUM COMPANY (US) 1991-08-28 EP disclosed
US-4988796-A Reaction of a dihaloaromatic sulfone with an alkali metal bisulfide and hydrogen sulfide with water, an amide an alkali metal carboxylate PHILLIPS PETROLEUM COMPANY (US) 1991-01-29 US disclosed
US-4003859-A CATALYST OF AN AMINE, AMIDE SALT AND DIBUTYL TIN(ALKANOATE) THE UPJOHN COMPANY (US) 1977-01-18 US disclosed