SCHEMBL3364633

SCHEMBL3364633

CC(=O)Oc1ccc(C)cc1.[NaH]

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.95
MAPT P10636 3/20 0.57
POLB P06746 2/20 0.57
PKM P14618 1/20 0.57
ELANE P08246 1/20 0.55
HSD17B10 Q99714 1/20 0.53
ALDH1A1 P00352 4/20 0.53
GAA P10253 2/20 0.52
HSP90AA1 P07900 1/20 0.52
KMT2A Q03164 4/20 0.50
MEN1 O00255 2/20 0.50
KDM4E B2RXH2 1/20 0.50
TTR P02766 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
GLA P06280 1/20 0.48
ACHE P22303 1/20 0.48
ESR1 P03372 1/20 0.47
PGR P06401 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28334142 0.98 LMNA (0.91) LMNAMAPTPOLBPKMELANE
Ethane SCHEMBL11785686 0.98 LMNA (0.91) LMNAMAPTPOLBPKMELANE
SCHEMBL280615 0.98 LMNA (1.00) LMNAMAPTPOLBPKMELANE
Ammonia Solution, Strong SCHEMBL27903026 0.95 LMNA (0.95) LMNAMAPTPOLBPKMELANE
SCHEMBL7798435 0.95 LMNA (0.95) LMNAMAPTPOLBPKMELANE
Hydrogen Sulfide SCHEMBL27637439 0.95 LMNA (0.95) LMNAMAPTPOLBPKMELANE
SCHEMBL19689201 0.95 LMNA (0.95) LMNAMAPTPOLBPKMELANE
SCHEMBL27835857 0.95 LMNA (0.95) LMNAMAPTPOLBPKMELANE
SCHEMBL27633104 0.95 LMNA (0.95) LMNAMAPTPOLBPKMELANE
Phosphine SCHEMBL27576228 0.95 LMNA (0.95) LMNAMAPTPOLBPKMELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7666566-B2 Electrophotographic toner and method of preparing the toner RICOH COMPANY, LTD. (JP) 2010-02-23 US disclosed
US-20050196691-A1 Electrophotographic toner and method of preparing the toner RICOH COMPANY, LTD. (JP) 2005-09-08 US disclosed