Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865696 | 0.76 | KMT2A (0.46) | HRH4 | |
| SCHEMBL27825032 | 0.71 | ALDH1A1 (0.45) | — | |
| SCHEMBL27834544 | 0.67 | ALDH1A1 (0.44) | — | |
| SCHEMBL27824926 | 0.66 | KMT2A (0.45) | DRD2 | |
| SCHEMBL27920304 | 0.65 | SMN1; SMN2 (0.51) | DRD4 | |
| SCHEMBL27800107 | 0.64 | KMT2A (0.47) | — | |
| SCHEMBL27851382 | 0.64 | LTA4H (0.38) | — | |
| SCHEMBL27791095 | 0.62 | ALOX15 (0.37) | — | |
| SCHEMBL27962911 | 0.61 | BIRC2 (0.33) | — | |
| SCHEMBL19785775 | 0.60 | XIAP (0.39) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105636956-A | Indole compound as inhibitor of necrosis | LG LIFE SCIENCES LTD | 2016-06-01 | — | — | CN | disclosed |