Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.40 |
| ▸ | HTR1A | P08908 | 8/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28061558 | 0.92 | HTR2A (0.40) | HTR2CHTR1A | |
| SCHEMBL28061588 | 0.92 | HTR2A (0.40) | HTR2CHTR1A | |
| SCHEMBL8613370 | 0.89 | DDB1 (0.31) | — | |
| SCHEMBL614853 | 0.78 | HTR2C (0.63) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL29691303 | 0.78 | HTR2C (0.63) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL27964417 | 0.77 | HTR2C (0.61) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| Hydrochloric Acid SCHEMBL4890789 | 0.77 | HTR2C (0.64) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL28061555 | 0.77 | JAK2 (0.37) | — | |
| SCHEMBL17046383 | 0.76 | DDB1 (0.31) | — | |
| SCHEMBL28061580 | 0.75 | RBP4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693645-B | Condensed heterocyclic compouds as ion channel modulators | 吉利德科学公司 | 2018-10-09 | — | — | CN | disclosed |
| CN-105693645-A | FUSED HETEROCYCLIC COMPOUNDS AS SODIUM CHANNEL MODULATORS | 吉利德科学公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-103649056-B | Fused heterocyclic compounds as modulators of ion channels | GILEAD SCIENCES, INC. (US) | 2016-04-27 | — | — | CN | disclosed |