SCHEMBL28061852

SCHEMBL28061852

CC(C)(C)C(=O)ON=Cc1csc(C2CCNCC2)n1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.39
BAZ2A Q9UIF9 2/20 0.39
HPGDS O60760 1/20 0.34
TLR9 Q9NR96 1/20 0.33
TLR8 Q9NR97 1/20 0.33
TLR7 Q9NYK1 1/20 0.33
GSK3B P49841 1/20 0.33
DYRK1A Q13627 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TMIGD3 P0DMS9 1/20 0.31
ADORA1 P30542 1/20 0.31
SHMT1 P34896 1/20 0.31
SHMT2 P34897 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27907736 1.00 AOC3 (0.39) AOC3BAZ2AHPGDSTLR9TLR8
SCHEMBL28020001 1.00 AOC3 (0.39) AOC3BAZ2AHPGDSTLR9TLR8
Tert-Butyl Formate SCHEMBL28061853 0.77 AOC3 (0.38) AOC3BAZ2AHPGDSTLR9TLR8
Tert-Butyl Formate SCHEMBL27907737 0.77 AOC3 (0.38) AOC3BAZ2AHPGDSTLR9TLR8
SCHEMBL27629638 0.75 AOC3 (0.41) AOC3BAZ2AHPGDSGSK3BDYRK1A
SCHEMBL27873725 0.74 AOC3 (0.50) AOC3BAZ2AHPGDSTLR9TLR8
SCHEMBL28007019 0.73 BAZ2A (0.41) AOC3BAZ2AHPGDSTLR9TLR8
SCHEMBL491234 0.72 HPGDS (0.44) AOC3BAZ2AHPGDSGSK3BDYRK1A
Hydrochloric Acid SCHEMBL29756 0.71 HPGDS (0.43) AOC3BAZ2AHPGDSGSK3BDYRK1A
Hydrochloric Acid SCHEMBL15717196 0.71 HPGDS (0.43) AOC3BAZ2AHPGDSGSK3BDYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105601627-B Heteroaryl piperidine and heteroaryl based piperazine derivative as fungicide 拜耳作物科学股份公司 2019-04-09 CN disclosed
CN-105601627-A Heteroarylpiperidine and -piperazine derivatives as fungicides BAYER CROPSCIENCE AG 2016-05-25 CN disclosed
CN-103153992-A Heteroarylpiperidine and piperazine derivatives as fungicides BAYER CROPSCIENCE AG 2013-06-12 CN disclosed