Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 4/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14379269 | 0.83 | PLAT (0.45) | AOC3BAZ2AGSK3BDYRK1AHPGDS | |
| SCHEMBL31705780 | 0.83 | PLAT (0.45) | AOC3BAZ2AGSK3BDYRK1AHPGDS | |
| SCHEMBL1228518 | 0.80 | BAZ2A (0.52) | AOC3BAZ2APLATCASP3CASP8 | |
| Bromide SCHEMBL5061856 | 0.79 | BAZ2A (0.51) | AOC3BAZ2APLATCASP3CASP8 | |
| Hydrochloric Acid SCHEMBL1119928 | 0.79 | RAB9A (0.53) | AOC3BAZ2APLATCASP3CASP8 | |
| SCHEMBL13997973 | 0.78 | BAZ2A (0.52) | AOC3BAZ2AGSK3BDYRK1AHPGDS | |
| Hydrochloric Acid SCHEMBL2516985 | 0.77 | BAZ2A (0.51) | AOC3BAZ2AGSK3BDYRK1AHPGDS | |
| SCHEMBL27789539 | 0.77 | GPR119 (0.47) | AOC3BAZ2AHPGDSMEN1KMT2A | |
| SCHEMBL491211 | 0.77 | HPGDS (0.46) | AOC3BAZ2AGSK3BDYRK1AHPGDS | |
| SCHEMBL27873725 | 0.77 | AOC3 (0.50) | AOC3BAZ2AHPGDSCASP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015026-B | The Compounds and methods for of the antiport suppressing NHE to mediate in treatment with fluid retention or salt over loading relevant disease and gastroenteropathy | MERCK PATENT GMBH (DE) | 2015-11-25 | — | — | CN | claimed |
| CN-102015026-A | Novel nip thiazole derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1 | MERCK PATENT GMBH | 2011-04-13 | — | — | CN | claimed |
| CN-109862896-A | For treating the Oxymethylene aryl compound of inflammatory gastrointestinal disease or gastrointestinal disorder | 西玛贝医药公司 | 2019-06-07 | — | — | CN | disclosed |
| CN-102015026-B | The Compounds and methods for of the antiport suppressing NHE to mediate in treatment with fluid retention or salt over loading relevant disease and gastroenteropathy | MERCK PATENT GMBH (DE) | 2015-11-25 | — | — | CN | disclosed |
| CN-101616586-B | Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders | CYMABAY THERAPEUTICS INC | 2014-08-13 | — | — | CN | disclosed |
| CN-102026636-B | Oxymethylene aryl compounds and uses thereof | METABOLEX INC | 2014-07-16 | — | — | CN | disclosed |
| CN-101987847-B | Novel heterocyclic NF-kB inhibitors | 4SC AG | 2012-10-10 | — | — | CN | disclosed |
| CN-101031567-B | Novel heterocyclic NF-kB inhibitors | 4SC Corp.,Ltd. (DE) | 2011-12-21 | — | — | CN | disclosed |
| CN-102026636-A | Oxymethylene aryl compounds and uses thereof | METABOLEX INC | 2011-04-20 | — | — | CN | disclosed |
| CN-102015026-A | Novel nip thiazole derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1 | MERCK PATENT GMBH | 2011-04-13 | — | — | CN | disclosed |
| CN-101987847-A | Novel heterocyclic NF-kB inhibitors | 4SC AG | 2011-03-23 | — | — | CN | disclosed |
| CN-101616586-A | The heterocyclic receptor agonists of treatment diabetes and metabolic disorder | METABOLEX INC | 2009-12-30 | — | — | CN | disclosed |
| CN-101405278-A | Novel heterocyclic NF-kB inhibitors | 4SC AG (DE) | 2009-04-08 | — | — | CN | disclosed |
| CN-101031567-A | Novel heterocyclic NF-kB inhibitors | 4SC AG (DE) | 2007-09-05 | — | — | CN | disclosed |
| CN-1809560-A | Thiazolylpiperidine derivatives as mtp inhibitors | MERCK PATENT GMBH (DE) | 2006-07-26 | — | — | CN | disclosed |