Urea

Urea

SCHEMBL28062092

C1CC2CCC12.NC(N)=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.50
ALDH1A1 P00352 2/20 0.50
LMNA P02545 2/20 0.50
OR51E2 Q9H255 1/20 0.50
ACHE P22303 1/20 0.36
EPHX1 P07099 3/20 0.35
ALOX5 P09917 4/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
NOS2 P35228 1/20 0.32
LDHA P00338 1/20 0.31
LDHB P07195 1/20 0.31
GRM1 Q13255 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
CYP2D6 P10635 1/20 0.31
GLI1 P08151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL159042 0.82 ALDH1A1 (0.53) TDP1ALDH1A1LMNAOR51E2EPHX1
SCHEMBL21122243 0.79 SMN1; SMN2 (0.44) TDP1ALDH1A1LMNAEPHX1NOS2
SCHEMBL2551174 0.74 EPHX1 (0.35) TDP1ALDH1A1LMNAOR51E2EPHX1
Urea C 13 SCHEMBL12476878 0.71
SCHEMBL18760074 0.71
Urea SCHEMBL8560069 0.71 LMNA (1.00) TDP1ALDH1A1LMNAOR51E2ACHE
Urea SCHEMBL411583 0.71
Urea SCHEMBL8434002 0.71 LMNA (1.00) TDP1ALDH1A1LMNAOR51E2ACHE
Urea SCHEMBL20641124 0.71 LMNA (1.00) TDP1ALDH1A1LMNAOR51E2ACHE
Urea SCHEMBL7756359 0.71 LMNA (1.00) TDP1ALDH1A1LMNAOR51E2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105842255-A A polishing layer analyzer and method 罗门哈斯电子材料CMP控股股份有限公司 2016-08-10 CN disclosed