Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31463538 | 0.79 | CYP19A1 (0.38) | KCNJ1KCNH2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL31463506 | 0.79 | KCNJ1 (0.43) | KCNJ1KCNH2MEN1KMT2AMAPT | |
| SCHEMBL1127509 | 0.79 | KCNJ1 (0.43) | KCNJ1KCNH2MEN1KMT2AMAPT | |
| SCHEMBL28062313 | 0.76 | KCNJ1 (0.43) | KCNJ1KCNH2MEN1KMT2AMAPT | |
| SCHEMBL3978869 | 0.76 | ALDH1A1 (0.46) | KCNJ1KCNH2MEN1KMT2AMAPT | |
| SCHEMBL8689842 | 0.76 | HSD17B10 (0.49) | KCNJ1KCNH2MEN1KMT2AMAPT | |
| SCHEMBL16371067 | 0.75 | AAK1 (0.49) | CYP19A1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL1644779 | 0.73 | HSD17B10 (0.49) | KCNJ1KCNH2MAPTHTTRAB9A | |
| SCHEMBL28056041 | 0.73 | PTPRC (0.44) | KCNJ1KCNH2MEN1KMT2AMAPT | |
| SCHEMBL4265596 | 0.73 | ALDH1A1 (0.49) | KCNJ1KCNH2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105517993-A | Aryl amide kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2016-04-20 | — | — | CN | disclosed |